Titel: Studien "Weight and Metabolic Outcomes..." och blodfetter Skrivet av: hemul skrivet 2010.09.06 - 05:14:35 Kostdoktorn skrev om studien Weight and Metabolic Outcomes After 2 Years on a Low-Carbohydrate
Versus Low-Fat Diet förra månaden. http://www.kostdoktorn.se/lagkolhydratkost-vinner-en-studie-till Vad han inte visste var att hela studien går att ladda ner här. :thumbsup: http://www.annals.org/content/suppl/2010/08/03/153.3.147.DC2/0000605-201008030-00005-v1.pdf Det måste vara något misstag, för klickar man på länken från summaryn så ombeds man betala. Nu har jag inte läst statistik och fattar inte allt, men klartext, det förstår jag. :lol: (Min fettext nedan) The low-carbohydrate diet produced a much greater increase in plasma HDL cholesterol concentration than did the low-fat diet at all assessments during the 2-year study. Plasma HDL cholesterol concentration increased by ap- proximately 20% at 6 months in the low-carbohydrate diet group, which persisted throughout the study and was more than twice the increase observed in the low-fat diet group. The magnitude of the changes observed in the low- carbohydrate group approximates that obtained with the maximal doses of nicotinic acid (niacin), the most effective HDL-raising pharmacologic intervention currently avail- able (28). The fact that the HDL cholesterol levels re- mained substantially elevated at 24 months, when the plasma triglyceride levels had returned to baseline in the low-carbohydrate group, argues against the conventional explanation that the increase in plasma HDL cholesterol concentration is solely secondary to a reduction in plasma triglyceride levels. The increased HDL cholesterol during a low-carbohydrate diet could result, at least in part, from the increased intake of dietary fat (29). Although weight loss and increased physical activity undoubtedly contrib- uted to the elevation of HDL cholesterol in both groups, the marked difference in HDL cholesterol between the 2 groups, despite similar weight loss, demonstrates that ma- cronutrient composition has independent effects on HDL. The mechanism responsible for the robust and sustained in- crease in HDL cholesterol levels among low-carbohydrate par- ticipants is unknown and will require additional mechanistic studies. The clinical implications of this increase in HDL cho- lesterol, which is conventionally believed to be beneficial, are uncertain and will probably depend on the mechanism re- sponsible for this effect. |